• Home
  • Our Mission
  • Clinical Trials
    • TARGIT-A Trial
    • TARGIT-US Trial
    • TARGIT-B Trial
    • TARGIT-DCIS Trial
    • Genetic Testing Registry
    • FROST Cryoablation Trial
    • Recent Publications
    • DCIS Cryoablation Study
  • Donate Here
  • Funding
  • Research
  • More
    • Home
    • Our Mission
    • Clinical Trials
      • TARGIT-A Trial
      • TARGIT-US Trial
      • TARGIT-B Trial
      • TARGIT-DCIS Trial
      • Genetic Testing Registry
      • FROST Cryoablation Trial
      • Recent Publications
      • DCIS Cryoablation Study
    • Donate Here
    • Funding
    • Research
  • Home
  • Our Mission
  • Clinical Trials
    • TARGIT-A Trial
    • TARGIT-US Trial
    • TARGIT-B Trial
    • TARGIT-DCIS Trial
    • Genetic Testing Registry
    • FROST Cryoablation Trial
    • Recent Publications
    • DCIS Cryoablation Study
  • Donate Here
  • Funding
  • Research

TARGIT-A Trial

Background

The purpose of this study is to evaluate whether a single fraction of radiotherapy given intra-operatively and targeted to the tissues at the highest risk of local recurrence is equivalent to standard post-operative external beam radiotherapy after breast conserving surgery in women with early stage breast cancer in terms of local relapse within the treated breast. This study has ended recruitment. 

Eligibility

Study Status: THIS STUDY IS NOW CLOSED TO ENROLLMENT.  THE FINAL RESULTS HAVE BEEN  PUBLISH, with Dr. Holmes as a co-author.  With an average of 8 year follow-up (including 18 years of follow-up of the first. enrolled patients), the TARGIT-A trial showed no difference in the breast cancer recurrence and survival rates between women who received targeted intraoperative radiotherapy and traditional whole breast radiation.


Click here to Read the publication: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61950-9/fulltext


Sponsors and Collaborators

University College London

National Institute for Health Research, United Kingdom

ClinicalTrials.gov Identifier:

 NCT00983684

Study Contact

Allison Zimmerman

Helen Rey Breast Cancer Research Foundation

Telephone: 818-539-1985 Fax: 818-539-1985

Copyright © 2021 Helen Rey Breast Cancer Research Foundation - All Rights Reserved.

Founded in 2017