Research

Ongoing Research Efforts

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Planned Projects

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Research Team

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Ongoing Research Efforts

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TARGIT-A Trial

An international randomized control trial to compare targeted intra-operative radiotherapy and conventional post-operative radiotherapy after conservative breast surgery for women with early stage breast cancer.

TARGIT-DCIS

A prospective nonrandomized trial designed to determine if patients with pure DCIS are considered eligible for concurrent IORT based on preoperative mammography and CE-MRI could be successfully treated using IORT with minimal need for additional therapy due to inadequate surgical margins or excessive tumor size.

TARGIT-US Trial

A phase IV pragmatic registry trial that studies the side effects of targeted intraoperative radiation therapy and how well it works in treating patients with early stage breast cancer following breast conserving surgery in patients in the United States.

TARGIT-B Trial

An international randomized controlled trial to compare targeted intra-operative radiotherapy boost with conventional external beam radiotherapy boost after lumpectomy for breast cancer in women with a high risk of local recurrence.

Cryoablation of Small Breast Tumors in Early Stage Breast Cancer (FROST)

A phase II, non-randomized trial to examine the use of cryoablation as an alternative to surgery in the treatment of early stage invasive breast cancer. The hypothesis is that cryoablation will complete ablation and destroy the tumor in a selected population of women who may otherwise be adequately treated with surgery.